Spastic paraplegia four (SPG4; also referred to as SPAST-HSP) is characterised by insidiously progressive bilateral lessen-limb gait spasticity. A lot more than fifty% of impacted people today have some weakness from the legs and impaired vibration sense on the ankles.????? ??? ????? ???? ????.????? ???? ??? ??? ??? ???? ?????.A chromosomal abnorma